10mM HEPES (pH7.5), 150mM NaCl, 100μg/ml BSA, 50% Glycerol
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Batch dependent (Please refer to the vial label for the specific concentration.)
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser378 conjugated to KLH
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
parkin RBR E3 ubiquitin protein ligase , AR-JP , LPRS2 , PARK2 , PDJ
Cytoplasm, cytosol , Nucleus , Endoplasmic reticulum , Mitochondrion
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]