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Perforin antibody

Anti-Perforin antibody used in IHC (Paraffin sections) (IHC-P). GTX64408
Anti-Perforin antibody used in IHC (Paraffin sections) (IHC-P). GTX64408
Anti-Perforin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64408
Anti-Perforin antibody used in Western Blot (WB). GTX64408

Cat. No. GTX64408

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Mouse, Rat
Package
100 μl ($399)
See all Perforin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 280-555 of human PRF1 (NP_001076585.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

perforin 1 , HPLH2 , P1 , PFP

Cellular Localization

Secreted,Cell membrane; Multi-pass membrane protein

Background

This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-Perforin antibody used in IHC (Paraffin sections) (IHC-P). GTX64408

GTX64408 IHC-P Image

IHC-P analysis of rat lung tissue using GTX64408 Perforin antibody.
Dilution : 1:100

Anti-Perforin antibody used in IHC (Paraffin sections) (IHC-P). GTX64408

GTX64408 IHC-P Image

IHC-P analysis of mouse spleen tissue using GTX64408 Perforin antibody.
Dilution : 1:100

Anti-Perforin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64408

GTX64408 ICC/IF Image

ICC/IF analysis of NIH/3T3 cells using GTX64408 Perforin antibody.
Blue : DAPI
Dilution : 1:100

Anti-Perforin antibody used in Western Blot (WB). GTX64408

GTX64408 WB Image

WB analysis of various sample lysates using GTX64408 Perforin antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399