GeneTex
United States (US)

Pez antibody [C2C3], C-term

GTX105769_40527_IHC_19011506_900.jpg
GTX105769_40527_WB_19011506_478.jpg

Cat No. GTX105769

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

135 kDa. ( Note )

Positive Control

A549 , HeLa , HepG2 , HCT116

Predict Reactivity

Mouse, Rat, Bovine(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human Pez. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

MGC126803 antibody, PEZ antibody, PTP36 antibody, PTPN14 antibody, cytoskeletal-associated protein tyrosine phosphatase antibody, protein-tyrosine phosphatase pez antibody, tyrosine-protein phosphatase non-receptor type 14 antibody, "protein tyrosine phosphatase, non-receptor type 14 antibody"

Cellular Localization

Cytoplasm , cytoskeleton

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. The specific function of this PTP has not yet been determined. [provided by RefSeq]
Show More +

Database

Research Area

DATA IMAGES
GTX105769_40527_IHC_19011506_900.jpg

GTX105769 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human lung papillory adenocarcinoma, using Pez(GTX105769) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX105769_40527_WB_19011506_478.jpg

GTX105769 WB Image

Sample (30 ug of whole cell lysate)
A: A549
B: HCT116
5% SDS PAGE
GTX105769 diluted at 1:1000

SDS
Glycerol.pdf
Thimerosal.pdf