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Placental Alkaline Phosphatase antibody [8A9]

Anti-Placental Alkaline Phosphatase antibody [8A9] used in IHC (Paraffin sections) (IHC-P). GTX01925

Cat. No. GTX01925

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 8A9

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($459)
See all Placental Alkaline Phosphatase products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Product Note

Immunohistochemical evidence (in house and published) supports reactivity with PLAP and also with PLAP-like enzyme.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Purified human placental alkaline phosphatase.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

alkaline phosphatase, placental , ALP , ALPI , IAP , PALP , PLAP , PLAP-1

Background

The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]

Database

Research Area

DATA IMAGES

Anti-Placental Alkaline Phosphatase antibody [8A9] used in IHC (Paraffin sections) (IHC-P). GTX01925

GTX01925 IHC-P Image

IHC-P analysis of human seminoma tissue using GTX01925 Placental Alkaline Phosphatase antibody [8A9]. Note the strong membrane and cytoplasmic staining of malignant cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 459