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Placental Alkaline Phosphatase antibody [SP15] (ready-to-use)

Anti-Placental Alkaline Phosphatase antibody [SP15] (ready-to-use) used in Immunohistochemistry (IHC). GTX79434
Anti-Placental Alkaline Phosphatase antibody [SP15] (ready-to-use) used in Immunohistochemistry (IHC). GTX79434

Cat. No. GTX79434

Reference 1

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 SP15

Isotype

 IgG

Application

 IHC-P, IHC

Reactivity

 Human
Package
6 ml ($399)
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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Product Note

This antibody reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. This antibody is highly specific to PLAP and shows no cross-reaction with other isoenzymes of alkaline phosphatases.

PROPERTIES

Form

Liquid

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encoding human Placental Alkaline Phosphatase (PLAP).

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_625732

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

alkaline phosphatase, placental , ALP , ALPI , IAP , PALP , PLAP , PLAP-1

Background

The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]

Database

Research Area

DATA IMAGES

Anti-Placental Alkaline Phosphatase antibody [SP15] (ready-to-use) used in Immunohistochemistry (IHC). GTX79434

GTX79434 IHC Image

Human Placenta stained with anti-PLAP antibody

Anti-Placental Alkaline Phosphatase antibody [SP15] (ready-to-use) used in Immunohistochemistry (IHC). GTX79434

GTX79434 IHC Image

Human Seminoma stained with anti-PLAP antibody

REFERENCE

Clone Reference

Zhu P et al. Mol Neurobiol 2019; Expression and Function of Mas-Related G Protein-Coupled Receptor D and Its Ligand Alamandine in Retina.
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REVIEW

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Package List Price ($)
$ 399