Plasma Kallikrein 1B antibody

Cat. No. GTX118926

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB
Reactivity	Mouse
Package	100 μl ($399), 25 μl ($169)

See all Plasma Kallikrein 1B products

Datasheet
Document

View product citations for antibody GTX118926 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:5000-1:20000

Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Positive Control

mouse kidney

Predict Reactivity

Human, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human Plasma Kallikrein 1B. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11176974

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

kallikrein B1 , KLK3 , PKK , PKKD , PPK

Cellular Localization

Secreted

Background

Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients. [provided by RefSeq]

Database

Gene ID: 3818 KLKB1
UniProt: P03952 KLKB1

Research Area

DATA IMAGES

GTX118926 WB Image

Sample (50 ug of whole cell lysate)
A: mouse kidney
7.5% SDS PAGE
GTX118926 diluted at 1:10000

REFERENCE

There are currently no references for Plasma Kallikrein 1B antibody (GTX118926). Be the first to share your publications with this product.

Submit a Reference

REVIEW

There are currently no reviews for Plasma Kallikrein 1B antibody (GTX118926). Be the first to share your experience with this product.

Submit a Review

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf

Package

List Price ($)

100 μl

$ 399

25 μl

$ 169

Qty