GeneTex
United States (US)

Plasminogen antibody [9E7]

Cat No. GTX10174

Host Mouse
Clonality Monoclonal
Clone Name 9E7
Isotype IgG2a
Application IHC-P, ELISA, Apuri
Reactivity Human
APPLICATION

Application Note

AP: Use at an assay dependent dilution. ELISA: Use at an assay dependent dilution. IHC-P: Use at an assay dependent dilution. Antigen retrieval is not essential but may optimise staining. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

91 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Preservative: 0.1% Sodium Azide; Constituents: PBS. pH 7.4

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

8.7mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length native protein (purified) (Human).

Purification

IgG fraction
Purity tested by electrophoresis.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

DKFZp779M0222

Background

Plasminogen is a plasma protein synthesised mostly in the liver. It consists of a single polypeptide chain and has a molecular weight of 88.5 kDa. The plasma concentration is usually in the range of 70 - 200mg/L. Plasminogen is activated by tissue-plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Plasmin consists of a heavy (A-) chain which contains 5 kringles and a light (B-) chain with the active site. Plasmin is a trypsin-like protease whose natural substrate is fibrin, with binding sites for fibrin residing on the kringles. Plasmin is essential for fibrinolysis and decreased fibrinolytic potential due to congenital defects in plasmin can lead to recurring thrombosis, thrombophlebitis and pulmonary embolism.

Database

Research Area

Package List Price ($)
$ 319