Plasminogen antibody (Biotin)

Cat. No. GTX27335

Host	Goat
Clonality	Polyclonal
Isotype	IgG
Application	WB, ELISA
Reactivity	Human
Package	1 mg ($399)

See all Plasminogen products

Datasheet
Document

View product citations for antibody GTX27335 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:2000-1:10000
ELISA	1:20000-1:100000

Not tested in other applications.

Calculated MW

91 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

20mM Potassium Phosphate, 150mM NaCl, 1% BSA

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

10 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Plasminogen collected from human plasma

Purification

IgG fraction
This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.

Conjugation

Biotin

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

plasminogen

Cellular Localization

Secreted

Background

Plasminogen is a plasma protein synthesised mostly in the liver. Plasma concentration is usually in the range of 70 - 200mg/L. Plasminogen is activated by tissue-plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.

Database

Gene ID: 5340 PLG
UniProt: P00747 PLG

Research Area

DATA IMAGES

GTX27335 WB Image

Goat anti Plasminogen antibody (GTX27335) was used to detect Plasminogen under reducing (R) and non-reducing (NR) conditions. Reduced samples of purified target proteins contained 4% BME and were boiled for 5 minutes. Samples of ~1ug of protein per lane were run by SDS-PAGE. Protein was transferred to nitrocellulose and probed with 1:3000 dilution of primary antibody (GTX27335).

REFERENCE

There are currently no references for Plasminogen antibody (Biotin) (GTX27335). Be the first to share your publications with this product.

Submit a Reference

REVIEW

There are currently no reviews for Plasminogen antibody (Biotin) (GTX27335). Be the first to share your experience with this product.

Submit a Review

SDS
Sodium Azide.pdf

Package

List Price ($)

1 mg

$ 399

Qty