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Plxdc2 antibody

Anti-Plxdc2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85419
Anti-Plxdc2 antibody used in Western Blot (WB). GTX85419
Anti-Plxdc2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85419

Cat. No. GTX85419

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all Plxdc2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Colon Tissue Lysate(GTX27928)

Product Note

This antibody is specific for Plxdc2 C-Terminus

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Plxdc2 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human Plxdc2.The immunogen is located within the last 50 amino acids of Plxdc2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

plexin domain containing 2 , TEM7R

Cellular Localization

Membrane

Background

Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57% amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.

Database

Research Area

DATA IMAGES

Anti-Plxdc2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85419

GTX85419 IHC-P Image

IHC-P analysis of human brain tissue using GTX85419 Plxdc2 antibody.
Working concentration : 50 μg/ml

Anti-Plxdc2 antibody used in Western Blot (WB). GTX85419

GTX85419 WB Image

WB analysis of human colon tissue lysate using GTX85419 Plxdc2 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Anti-Plxdc2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85419

GTX85419 IHC-P Image

IHC-P analysis of human brain tissue using GTX85419 Plxdc2 antibody.
Working concentration : 2.5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399