Polycystin 2 antibody

Cat. No. GTX04499

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, FACS
Reactivity	Human, Mouse, Rat
Package	100 μg ($469)

See all Polycystin 2 products

Datasheet

View product citations for antibody GTX04499 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	0.25-0.5μg/ml
IHC-P	0.5-1μg/ml
FACS	1-3μg/1x10⁶ cells
Note : IHC-P By heat

Not tested in other applications.

Calculated MW

110 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4

Preservative

0.05mg Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

E.coli-derived human Polycystin 2/PKD2 recombinant protein (Position: S829-R893).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

polycystin 2, transient receptor potential cation channel , APKD2 , PC2 , PKD4 , Pc-2 , TRPP2

Cellular Localization

Endoplasmic reticulum membrane , Cell membrane , Basolateral cell membrane , Golgi apparatus

Background

This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]

Database

Gene ID: 5311 PKD2
UniProt: Q13563 PKD2

Research Area

DATA IMAGES

GTX04499 WB Image

WB analysis of various lysates using GTX04499 Polycystin 2 antibody.
Lane 1 : U87-MG whole cell lysate
Lane 2 : Rat spleen tissue lysate
Lane 3 : Mouse thymus tissue lysate
Lane 4 : Mouse lung tissue lysate
Lane 5 : SP20 whole cell lysate
Loading : 50 μg
Dilution : 0.5 μg/mL

GTX04499 IHC-P Image

IHC-P analysis of human renal cancer tissue using GTX04499 Polycystin 2 antibody.
Antigen retrieval : Heat mediated citrate buffer (pH 6)
Dilution : 1 μg/mL

GTX04499 FACS Image

FACS analysis of A549 cells using GTX04499 Polycystin 2 antibody.
Blue : Primary antibody
Green : Isotype control
Red : Unlabelled sample
Dilution : 1 μg/10⁶ cells

REFERENCE

There are currently no references for Polycystin 2 antibody (GTX04499). Be the first to share your publications with this product.

Submit a Reference

REVIEW

There are currently no reviews for Polycystin 2 antibody (GTX04499). Be the first to share your experience with this product.

Submit a Review

Package

List Price ($)

100 μg

$ 469

Qty