GeneTex
United States (US)

Prealbumin antibody [N1C3]

GTX100577_40016_WB_M_Liver_19011506_485.jpg
GTX100577_40016_20180504_WB_R_plasma_19011506_108.jpg
GTX100577_40016_20151105_WB_H_plasma_19011506_989.jpg

Cat No. GTX100577

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

16 kDa. ( Note )

Positive Control

Human plasma , Mouse liver , rat plasma

Predict Reactivity

Sheep, Bovine, Cat, Pig, Chimpanzee, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length human Prealbumin Recombinant protein.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Transthyretin,Attr,Cts,Cts1,Hel111,Hst2651,Palb,Tbpa,Ttr

Cellular Localization

Secreted , Cytoplasm

Background

This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX100577_40016_WB_M_Liver_19011506_485.jpg

GTX100577 WB Image

Sample (50 µg of whole cell lysate)
A: mouse liver
15% SDS PAGE
GTX100577 diluted at 1:500
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX100577_40016_20180504_WB_R_plasma_19011506_108.jpg

GTX100577 WB Image

Rat plasma (50 µg) was separated by 15% SDS-PAGE, and the membrane was blotted with Prealbumin antibody [N1C3] (GTX100577) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX100577_40016_20151105_WB_H_plasma_19011506_989.jpg

GTX100577 WB Image

Human tissue extract (30 µg) was separated by 15% SDS-PAGE, and the membrane was blotted with Transthyretin antibody [N1C3] (GTX100577) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169