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ProDynorphin antibody

Anti-ProDynorphin antibody used in Immunohistochemistry (IHC). GTX10280
Anti-ProDynorphin antibody used in Immunohistochemistry (IHC). GTX10280
Anti-ProDynorphin antibody used in Immunohistochemistry (IHC). GTX10280

Cat. No. GTX10280

Reference 4

Host

 Guinea pig

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-Fr, IHC

Reactivity

 Mouse, Rat
Package
50 μl ($399)
See all ProDynorphin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr 1:250-1:1000
IHC Assay dependent
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS, 30% Glycerol

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

SQENPNTYSEDLDV. Corresponding to residues 235-248 of the rat proDynorphin.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_380971

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

prodynorphin

Background

The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine.

Database

Research Area

DATA IMAGES

Anti-ProDynorphin antibody used in Immunohistochemistry (IHC). GTX10280

GTX10280 IHC Image

IHC analysis of rat hypothalamus tissue using GTX10280 ProDynorphin antibody.

Anti-ProDynorphin antibody used in Immunohistochemistry (IHC). GTX10280

GTX10280 IHC Image

IHC analysis of mouse spinal cord tissue using GTX10280 ProDynorphin antibody.

Anti-ProDynorphin antibody used in Immunohistochemistry (IHC). GTX10280

GTX10280 IHC Image

IHC analysis of ipsilateral L5 DRG, dorsal spinal cords and sciatic nerves of SNL rats using GTX10280 ProDynorphin antibody. Immunofluorescent labeling was done 14 d after sham or SNL surgery and treatment with vehicle or artemin starting on day 3 after surgery.

REFERENCE

Application Reference

Yang WZ et al. Sci Adv 2020; 6 (36) Parabrachial neuron types categorically encode thermoregulation variables during heat defense.
Ghule A et al. Sci Rep 2020; 10 (1) : 3821 Modulation of feeding behavior and metabolism by dynorphin.
Reactivity : Mouse
Long I et al. Korean J Pain 2013; 26 (3) : 255-64 the effects of pre-emptive administration of * and norbni on pain behavior, c-fos, and prodynorphin protein expression in the rat spinal cord after formalin-induced pain is modulated by the dream protein.
Application : IHC-Fr
Reactivity : Rat
Long I et al. Neurochem Res 2011; 36 (3) : 533-9 Increases in mRNA and DREAM protein expression in the rat spinal cord after formalin induced pain.
Application : IHC
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399