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Progesterone Receptor antibody [16]

Anti-Progesterone Receptor antibody [16] used in IHC (Paraffin sections) (IHC-P). GTX01926

Cat. No. GTX01926

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 16

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($679)
See all Progesterone Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100–1:200

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. High temperature antigen retrieval using 0.01 M citrate retrieval solution (pH 6.0) is recommended.
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Product Note

This antibody reacts with both A and B forms of human progesterone receptor in Western blotting procedures, but only the A form is detected in immunohistochemical procedures.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein, corresponding to the N-terminal region of the A form of human progesterone receptor.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

progesterone receptor , NR3C3 , PR

Cellular Localization

Nucleus , Cytoplasm

Background

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-Progesterone Receptor antibody [16] used in IHC (Paraffin sections) (IHC-P). GTX01926

GTX01926 IHC-P Image

IHC-P analysis of breast carcinoma tissue using GTX01926 Progesterone Receptor antibody [16]. Note the nuclear staining in a proportion of tumor cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 679