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Progesterone Receptor antibody [MSVA-570R] HistoMAX™

Recombinant antibody HistoMAX
Anti-Progesterone Receptor antibody [MSVA-570R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04431
Anti-Progesterone Receptor antibody [MSVA-570R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04431
Anti-Progesterone Receptor antibody [MSVA-570R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04431

Cat. No. GTX04431

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 MSVA-570R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($899),
100 μl ($299)
See all Progesterone Receptor products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50-1:100

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Positive Control

Uterine cervix: almost all columnar epithelial cells, basal squamous epithelial cells and most of the stromal cells must show a strong nuclear staining with only minimal cytoplasmic staining.

Negative Control

Tonsil: PR immunostaining should be absent in all epithelial and non-epithelial cells.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment (around aa 1-200) of human PGR

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

progesterone receptor , NR3C3 , PR

Cellular Localization

Nucleus , Cytoplasm

Background

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-Progesterone Receptor antibody [MSVA-570R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04431

GTX04431 IHC-P Image

IHC-P analysis of human endometrioid carcinoma (EC) tissue using GTX04431 Progesterone Receptor antibody [MSVA-570R] HistoMAX™.
Endometroid carcinoma of the ovary depicting a strong progesterone receptor immunostaining of all tumor cells.

Anti-Progesterone Receptor antibody [MSVA-570R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04431

GTX04431 IHC-P Image

IHC-P analysis of human invasive breast cancer of no special type (NST) tissue using GTX04431 Progesterone Receptor antibody [MSVA-570R] HistoMAX™.
Invasive breast cancer of no special type (NST) with strong progesterone receptor immunostaining in 100 of tumor cells.

Anti-Progesterone Receptor antibody [MSVA-570R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04431

GTX04431 IHC-P Image

IHC-P analysis of human endocervix tissue using GTX04431 Progesterone Receptor antibody [MSVA-570R] HistoMAX™.
Strong progesterone receptor immunostaining in epithelial and stromal cells of the endocervix.

REFERENCE

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REVIEW

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Package List Price ($)
$ 899
$ 299