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Progesterone Receptor antibody [SPM566]

Anti-Progesterone Receptor antibody [SPM566] used in IHC (Paraffin sections) (IHC-P). GTX34981

Cat. No. GTX34981

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 SPM566

Isotype

 IgG1

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all Progesterone Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml for 2 hours at Room Temp
IHC-P 1-2μg/ml for 30 min at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Product Note

This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human Progesterone Receptor protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NR3C3 , PGR , PR , progesterone receptor , Progesterone Receptor

Cellular Localization

Nucleus,Cytoplasm,Mitochondrion outer membrane

Background

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-Progesterone Receptor antibody [SPM566] used in IHC (Paraffin sections) (IHC-P). GTX34981

GTX34981 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX34981 Progesterone Receptor antibody [SPM566].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529