Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Immunogen Sequence: GI # 31981492, sequence 61-350 Recombinant progesterone receptor
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
progesterone receptor , NR3C3 , PR
Cellular Localization
Nucleus,Cytoplasm
Background
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Progesterone receptor. a member of the steroid receptor superfamily. mediates the physiologic effects of progesterone. The PGR gene uses separate promoters and translational start sites to produce 2 isoforms. PRA and PRB. which are identical except for an additional 165 amino acids present only in the N terminus of PRB. Although PRA and PRB share several structural domains. they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap.[supplied by OMIM].
Database
Research Area