APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| Assay dependent |
| Assay dependent |
| Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
Recognises amino acid residues 3-43 (MARLGPEWSQPMKR) of the prosegment of prorenin.
PROPERTIES
Form
Liquid
Buffer
0.05M Sodium Phosphate pH 6.6, 0.1M NaCl, 1mM EDTA
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant full length wild-type human protein (Glycosylated).
Purification
Protein A purified
From tissue culture supernatant
Conjugation
Fluorescein isothiocyanate (FITC)
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
HNFJ2,REN,renin,Renin,Prorenin
Cellular Localization
Secreted,Membrane
Background
Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]
Database
Research Area
REFERENCE
There are currently no references for Prorenin antibody [4B5-E3] (FITC) (GTX79680). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Prorenin antibody [4B5-E3] (FITC) (GTX79680). Be the first to share your experience with this product.
![Anti-Cardiac Troponin I antibody [N1C3] used in IHC (Paraffin sections) (IHC-P). GTX109331](/upload/website/prouct_img/small/GTX109331/GTX109331_40100_20200306_IHC-P-FL_M_20031101_187.jpg "Anti-Cardiac Troponin I antibody [N1C3] used in IHC (Paraffin sections) (IHC-P). GTX109331")
