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Proteasome 20S beta 3 antibody

Anti-Proteasome 20S beta 3 antibody used in IHC (Paraffin sections) (IHC-P). GTX66592
Anti-Proteasome 20S beta 3 antibody used in Western Blot (WB). GTX66592
Anti-Proteasome 20S beta 3 antibody used in IHC (Paraffin sections) (IHC-P). GTX66592
Anti-Proteasome 20S beta 3 antibody used in IHC (Paraffin sections) (IHC-P). GTX66592

Cat. No. GTX66592

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Proteasome 20S beta 3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 1-205 of human PSMB3 (NP_002786.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

proteasome subunit beta 3 , HC10-II

Cellular Localization

Cytoplasm,Nucleus

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12. Alternative splicing results in multiple transcript variants [provided by RefSeq, Sep 2013]

Database

Research Area

DATA IMAGES

Anti-Proteasome 20S beta 3 antibody used in IHC (Paraffin sections) (IHC-P). GTX66592

GTX66592 IHC-P Image

IHC-P analysis of rat lung tissue using GTX66592 Proteasome 20S beta 3 antibody.
Dilution : 1:100

Anti-Proteasome 20S beta 3 antibody used in Western Blot (WB). GTX66592

GTX66592 WB Image

WB analysis of various sample lysates using GTX66592 Proteasome 20S beta 3 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Proteasome 20S beta 3 antibody used in IHC (Paraffin sections) (IHC-P). GTX66592

GTX66592 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX66592 Proteasome 20S beta 3 antibody.
Dilution : 1:100

Anti-Proteasome 20S beta 3 antibody used in IHC (Paraffin sections) (IHC-P). GTX66592

GTX66592 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX66592 Proteasome 20S beta 3 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399