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Proteasome 26S S3 antibody

Anti-Proteasome 26S S3 antibody used in IHC (Paraffin sections) (IHC-P). GTX33430
Anti-Proteasome 26S S3 antibody used in Western Blot (WB). GTX33430

Cat No. GTX33430

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Rat
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A synthetic peptide of human PSMD3

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

proteasome 26S subunit, non-ATPase 3 , P58 , RPN3 , S3 , TSTA2

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count. [provided by RefSeq, Jul 2012]

Database

Research Area

DATA IMAGES

Anti-Proteasome 26S S3 antibody used in IHC (Paraffin sections) (IHC-P). GTX33430

GTX33430 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX33430 Proteasome 26S S3 antibody.
Dilution : 1:200

Anti-Proteasome 26S S3 antibody used in Western Blot (WB). GTX33430

GTX33430 WB Image

WB analysis of various samples using GTX33430 Proteasome 26S S3 antibody.
Dilution : 1:400
Loading : 25μg per lane

REFERENCE

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REVIEW

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Package List Price ($)
$ 329