GeneTex
United States (US)

QDPR antibody

GTX104428_40681_IHC_19011506_405.jpg
GTX104428_40681_WB_M_Liver_19011506_317.jpg
GTX104428_40681_WB_19011506_671.jpg

Cat No. GTX104428

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

Positive Control

Jurkat , mouse liver

Predict Reactivity

Rat, Rabbit, Bovine, Chicken, Pig(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.92mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human QDPR. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

DHPR antibody, FLJ42391 antibody, PKU2 antibody, SDR33C1 antibody, QDPR antibody, HDHPR antibody, "short chain dehydrogenase/reductase family 33C, member 1 antibody", dihydropteridine reductase antibody, "6,7-dihydropteridine reductase antibody", quinoid dihydropteridine reductase antibody

Background

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX104428_40681_IHC_19011506_405.jpg

GTX104428 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using QDPR(GTX104428) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX104428_40681_WB_M_Liver_19011506_317.jpg

GTX104428 WB Image

Sample (50 ug of whole cell lysate)
A: mouse Liver
12% SDS PAGE
GTX104428 diluted at 1:1000

GTX104428_40681_WB_19011506_671.jpg

GTX104428 WB Image

Sample (30 ug of whole cell lysate)
A: Jurkat
12% SDS PAGE
GTX104428 diluted at 1:1000

SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169