RAB27A antibody [N1C3]

Name: RAB27A antibody [N1C3]
Brand: GeneTex
SKU: GTX109180
Price: 399.00 USD
Rating: 5 (1 reviews)

Anti-RAB27A antibody [N1C3] used in Western Blot (WB). GTX109180

Cat. No. GTX109180

Reference 2

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human
Package	100 μl ($399), 25 μl ($169)

See all RAB27A products

View product citations for antibody GTX109180 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	Assay dependent
IHC-P	Assay dependent

Not tested in other applications.

Calculated MW

25 kDa. ( Note )

Product Note

Knockout/Knockdown validation was supported by customer review data.
Knockdown/Knockout validation was supported by customer review data.

Predict Reactivity

Mouse, Rat, Zebrafish, Bovine, Dog, Chicken, Pig, Xenopus tropicalis, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length human RAB27A Recombinant protein.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2037814

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

RAB27A, member RAS oncogene family , GS2 , HsT18676 , RAB27 , RAM

Cellular Localization

Membrane; Lipid-anchor , Melanosome

Background

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq]

Database

Gene ID: 5873 RAB27A
UniProt: P51159 RAB27A

Research Area

DATA IMAGES

GTX109180 WB Image

The data was published in the journal Mol Cancer in 2017.PMID: 28784136

REFERENCE

Application Reference

Choi JY et al. Cell Commun Signal 2024; 22 (1) : 190 Tumor-derived miR-6794-5p enhances cancer growth by promoting M2 macrophage polarization.

Chang YC et al. Mol Cancer 2017; 16 (1) : 135 Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis.

Application : WB, IHC-P

Reactivity : Human

Submit a Reference

REVIEW