*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
RAB3GAP2 Antibody detects endogenous levels of total RAB3GAP2 protein.
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
The antiserum was produced against synthesized peptide derived from human RAB3GAP2.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Rab3-GAP p150, Rab3 GTPase-activating protein 150 kDa subunit, RAB3GAP2, Rab3 GTPaseactivating protein150 kDa subunit, Rab3 GTPaseactivating protein 150 kDa subunit, Rab3-GAP regulatory subunit, RGAP-iso, Rab3GAP p150, RGAPiso, RAB3-GAP150, Rab3GAP regulatory subunit, RAB3GAP150, RGAP iso, RAB3 GAP150, Rab3 GAP p150, Rab3 GAP regulatory subunit
In neurons, it is enriched in the synaptic soluble fraction.
Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.