GeneTex
United States (US)

RAB3GAP2 antibody

RAB3GAP2-antibody-GTX87680-WB-1_18121411_255.jpg
RAB3GAP2-antibody-GTX87680-IHC-1_18121411_562.jpg

Cat No. GTX87680

Host Rabbit
Clonality Polyclonal
Application WB, IHC-P, ELISA, IHC
Reactivity Human, Mouse, Rat, Monkey
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P Assay dependent
ELISA Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

155 kDa. ( Note )

Specificity/Sensitivity

RAB3GAP2 Antibody detects endogenous levels of total RAB3GAP2 protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human RAB3GAP2.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Rab3-GAP p150, Rab3 GTPase-activating protein 150 kDa subunit, RAB3GAP2, Rab3 GTPaseactivating protein150 kDa subunit, Rab3 GTPaseactivating protein 150 kDa subunit, Rab3-GAP regulatory subunit, RGAP-iso, Rab3GAP p150, RGAPiso, RAB3-GAP150, Rab3GAP regulatory subunit, RAB3GAP150, RGAP iso, RAB3 GAP150, Rab3 GAP p150, Rab3 GAP regulatory subunit

Cellular Localization

In neurons, it is enriched in the synaptic soluble fraction.

Background

Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
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Database

DATA IMAGES
RAB3GAP2-antibody-GTX87680-WB-1_18121411_255.jpg

GTX87680 WB Image

Western blot analysis of extracts from COS cells, using RAB3GAP2 Antibody. The lane on the right is treated with the synthesized peptide.

RAB3GAP2-antibody-GTX87680-IHC-1_18121411_562.jpg

GTX87680 IHC-P Image

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using RAB3GAP2 Antibody. The picture on the right is treated with the synthesized peptide.

Reference
Package List Price ($)
$ 349