GeneTex
United States (US)

RAD23B antibody

RAD23B-antibody-GTX86971-WB-1_18121411_383.jpg

Cat No. GTX86971

Host Rabbit
Clonality Polyclonal
Application WB, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

We recommend the following starting dilutions:

WB: 1:500~1:1000
ELISA: 1:20000

Optimal dilutions should be determined experimentally by the end user.

Calculated MW

43 kDa. ( Note )

Specificity/Sensitivity

RAD23B Antibody detects endogenous levels of total RAD23B protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human RAD23B.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Rad23 Homolog B, Nucleotide Excision Repair Protein,Hhr23B,Hr23B,P58,Rad23B

Background

Plays a central role both in proteosomal degradation of misfolded proteins and DNA repair. Central component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Involved in DNA excision repair by stabilizing XPC protein. May play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage-processing enzymes.

Database

DATA IMAGES
RAD23B-antibody-GTX86971-WB-1_18121411_383.jpg

GTX86971 WB Image

Western blot analysis of extracts from A549/HuvEc cells, using RAD23B Antibody. The lane on the right is treated with the synthesized peptide.

Package List Price ($)
$ 339