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RAGE antibody [8D11]

Cat. No. GTX52973

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 8D11

Isotype

 IgG2

Application

 WB, Functional Assay, Neutralizing/Inhibition

Reactivity

 Human
Package
100 μg ($399)
See all RAGE products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
Functional Assay Assay dependent
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant RAGE EC domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

RRID

AB_2887809

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

AGER , RAGE , SCARJ1 , advanced glycosylation endproduct specific receptor , advanced glycosylation end-product specific receptor

Cellular Localization

Cell membrane,Secreted

Background

The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]

Database

Research Area

REFERENCE

Application Reference

Kido R et al. J Periodontal Res 2020; Advanced glycation end-products increase lipocalin 2 expression in human oral epithelial cells.
Application : Functional Assay
Reactivity : Human
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399