GeneTex
United States (US)

RAGE antibody

GTX16592_1372_WB_18121410_142.jpg
GTX16592_24_FACS_18121410_756.jpg
GTX16592_656_IHC-P_18121410_532.jpg

Cat No. GTX16592

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, FACS
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
IHC-P 1:10-1:50
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

43 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human AGER (RAGE).

Purification

Protein A purified, followed by peptide affinity purification.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Advanced Glycosylation End-Product Specific Receptor,Rage,Scarj1,Ager

Background

The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]

Database

Research Area

DATA IMAGES
GTX16592_1372_WB_18121410_142.jpg

GTX16592 WB Image

WB analysis of mouse lung tissue lysate (35ug/lane) using GTX16592 RAGE antibody.

GTX16592_24_FACS_18121410_756.jpg

GTX16592 FACS Image

FACS analysis of U251 cells using GTX16592 RAGE antibody.
Top histogram : negative control
Bottom histogram : U251 cells

GTX16592_656_IHC-P_18121410_532.jpg

GTX16592 IHC-P Image

IHC-P analysis of human lung carcinoma using GTX16592 RAGE antibody.