GeneTex
United States (US)

RAIDD antibody, C-term

RAIDD-antibody-C-term_WB_GTX28425-1_18121411_665.jpg
RAIDD-antibody-C-term_IHC-P_GTX28425-1_18121411_848.jpg

Cat No. GTX28425

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

Western blot at 1:500 to 1:1000 dilution.

Positive Control

Whole cell lysate from HeLa cells A major 22 kDa band should be detected
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

0.5mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide corresponding to amino acids 181 to199 of human RAIDD (1).

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Background

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologousprotein with DD) and CRADD (caspase and RIP adapter with DD)(1,2). RAIDD contains a DD and a CARD (for caspase recruitment domain), which interact with RIP and caspase, respectively, to transduce death signals (1,3). RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.

Research Area

DATA IMAGES
RAIDD-antibody-C-term_WB_GTX28425-1_18121411_665.jpg

GTX28425 WB Image

Western blot analysis of RAIDD in HeLa total cell lysate with Anti-RAIDD (CT) (Cat. No.GTX28425) at 1:500 dilution.

RAIDD-antibody-C-term_IHC-P_GTX28425-1_18121411_848.jpg

GTX28425 IHC-P Image

Immunohistochemical staining of RAIDD in human kidney with RAIDD antibody (GTX28425) at 10μg/ml.

Package List Price ($)
$ 329