PBS pH7.2 with 10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl, 0.1% bovine serum albumin, and 0.02% sodium azide
Store the peptide at -20˚C, stable for one year.
0.20 mg/ml (Please refer to the vial label for the specific concentration.)
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Casp2 And Ripk1 Domain Containing Adaptor With Death Domain,Mrt34,Raidd,Cradd
Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNFfamily through their death domain (DD) containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP associated ICH1/CED3 homologous protein with DD) and CRADD (caspase and RIP adapter with DD). RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR1.