GeneTex

  • Country / Location Selection

United States (US)

RANBP2 antibody

Anti-RANBP2 antibody used in Western Blot (WB). GTX22938
Anti-RANBP2 antibody used in IHC (Frozen sections) (IHC-Fr). GTX22938

Cat. No. GTX22938

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-Fr, IHC

Reactivity

 Human, Bovine
Package
100 μg ($399)
See all RANBP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/ml
IHC-Fr 10 μg/ml
IHC Assay dependent
Not tested in other applications.

Calculated MW

358 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to residues M(1) R R S K A D V E R Y I A S V Q G S(18) of human RanBP2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

RAN binding protein 2 , ADANE , ANE1 , IIAE3 , NUP358 , TRP1 , TRP2

Cellular Localization

Nucleus

Background

RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-RANBP2 antibody used in Western Blot (WB). GTX22938

GTX22938 WB Image

WB analysis of human retinal extracts using GTX22938 RANBP2 antibody.

Anti-RANBP2 antibody used in IHC (Frozen sections) (IHC-Fr). GTX22938

GTX22938 IHC-Fr Image

IHC-Fr analysis of bovine retina tissue using GTX22938 RANBP2 antibody.

REFERENCE

There are currently no references for RANBP2 antibody (GTX22938). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for RANBP2 antibody (GTX22938). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399