APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:3000 |
Not tested in other applications.
Calculated MW
Positive Control
CCL5 transfected 293T cell
Predict Reactivity
Mouse, Rat, Bovine, Dog, Guinea pig, Pig, Rhesus Monkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.42 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RANTES. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_1949882
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-C motif chemokine ligand 5 , D17S136E , RANTES , SCYA5 , SIS-delta , SISd , TCP228 , eoCP
Cellular Localization
Secreted
Background
This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. [provided by RefSeq]
Database
Research Area
DATA IMAGES
![Anti-RANTES antibody [N2C3] used in Western Blot (WB). GTX108441](/templates/default/js/lightbox/images/loading.gif "Anti-RANTES antibody [N2C3] used in Western Blot (WB). GTX108441")
|
GTX108441 WB Image
Western Blot analysis of CCL5 expression in transfected 293T cell line by CCL5 polyclonal antibody.
A: Non-transfected lysate.
B: CCL5 transfected lysate.
15% SDS PAGE
GTX108441 diluted at 1:500
|
REFERENCE
There are currently no references for RANTES antibody [N2C3] (GTX108441). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for RANTES antibody [N2C3] (GTX108441). Be the first to share your experience with this product.
![Anti-RANTES antibody [N2C3] used in Western Blot (WB). GTX108441](/upload/website/prouct_img/small/GTX108441/GTX108441_WB_w_23060120_822.webp "Anti-RANTES antibody [N2C3] used in Western Blot (WB). GTX108441")
![Anti-RANTES antibody [N2C3] used in Western Blot (WB). GTX108441](/upload/website/prouct_img/normal/GTX108441/GTX108441_WB_w_23060120_822.webp "Anti-RANTES antibody [N2C3] used in Western Blot (WB). GTX108441")