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RANTES antibody

Anti-RANTES antibody used in Western Blot (WB). GTX27198

Cat. No. GTX27198

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Mouse, Rat
Package
50 μg ($399)
See all RANTES products

APPLICATION

Application Note

WB: Use at a dilution of 1/2000. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

11 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Recombinant fragment, corresponding to amino acids 1-70 of mature Rat RANTES.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-C Motif Chemokine Ligand 5 , Rantes , Scya5 , Ccl5

Cellular Localization

Secreted

Background

RANTES (regulated upon activation, normal T-cell expressed and secreted) is a 70-amino acid CC chemokine originally cloned from T cell-specific sequences-enriched cDNA libraries (ref 1-3). Both human and murine RANTES are chemotactic for monocytes. Human RANTES is also a chemoattractant for T cells and eosinophils, as well as an activator of basophils for histamine release (ref 4). In contrast to other CC chemokines, RANTES is only slowly expressed after activation of leukocytes. It is involved in a number of pathological conditions like chronic inflammation and autoimmune diseases (ref 2).

Research Area

DATA IMAGES

Anti-RANTES antibody used in Western Blot (WB). GTX27198

GTX27198 WB Image

RANTES detected by WB in RAW264.7 cells treated with LPS(15h). Lane1: lysate; Lane2: supernatant

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399