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RASD2 antibody

Anti-RASD2 antibody used in Western Blot (WB). GTX47859
Anti-RASD2 antibody used in IHC (Paraffin sections) (IHC-P). GTX47859
Anti-RASD2 antibody used in IHC (Paraffin sections) (IHC-P). GTX47859
Anti-RASD2 antibody used in IHC (Paraffin sections) (IHC-P). GTX47859
Anti-RASD2 antibody used in IHC (Paraffin sections) (IHC-P). GTX47859

Cat No. GTX47859

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, IP, ELISA, IHC

Reactivity

Human, Mouse, Rat, Monkey
Package
100 μg ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500
IHC-P Assay dependent
IP 1:100
ELISA 1:10000
IHC 1:10000
Not tested in other applications.

Calculated MW

30 kDa. ( Note )

Specificity/Sensitivity

This antibody will not cross react with RASD1/Dexras.

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine pH 7.4-7.9, 30% glycerol, BSA, 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide taken within amino acid region 250-317 on RASD2 protein.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

RASD family member 2 , Rhes , TEM2

Cellular Localization

Cell membrane

Background

This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-RASD2 antibody used in Western Blot (WB). GTX47859

GTX47859 WB Image

WB analysis of wide type (lane 1) and RASD2 KO (lane 2) mouse striatum tissue lysates using GTX47859 RASD2 antibody.

Anti-RASD2 antibody used in IHC (Paraffin sections) (IHC-P). GTX47859

GTX47859 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX47859 RASD2 antibody.
Dilution : 1:100

Anti-RASD2 antibody used in IHC (Paraffin sections) (IHC-P). GTX47859

GTX47859 IHC-P Image

IHC-P analysis of rat lung tissue using GTX47859 RASD2 antibody.
Dilution : 1:100

Anti-RASD2 antibody used in IHC (Paraffin sections) (IHC-P). GTX47859

GTX47859 IHC-P Image

IHC-P analysis of rat lung tissue using GTX47859 RASD2 antibody.
Dilution : 1:100

Anti-RASD2 antibody used in IHC (Paraffin sections) (IHC-P). GTX47859

GTX47859 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX47859 RASD2 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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