GeneTex

  • Country / Location Selection

United States (US)

ROCK1 blocking peptide

Cat. No. GTX31836-PEP

Application

 Neutralizing/Inhibition
Package
50 μg ($139)
See all ROCK1 products
PRODUCT

Summary

ROCK1 peptide is used for blocking the activity of ROCK1 antibody (catalog number GTX31836).

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Rho Associated Coiled-Coil Containing Protein Kinase 1 , P160Rock , Rock-I , Rock1

Background

This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq, Jul 2008]

Research Area

REFERENCE

There are currently no references for ROCK1 blocking peptide (GTX31836-PEP). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for ROCK1 blocking peptide (GTX31836-PEP). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 139