APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1000 |
Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
This antibody is specific for alpha isotypes.
PROPERTIES
Form
Liquid
Buffer
PBS, 0.1% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide corresponding to residues K(541) E L F T S E F E P A M Q I D G(556) of human ROR alpha.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
RRID
AB_11168482
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
RAR related orphan receptor A , IDDECA , NR1F1 , ROR1 , ROR2 , ROR3 , RZR-ALPHA , RZRA
Cellular Localization
Nucleus
Background
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]
Database
Research Area
DATA IMAGES
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GTX79267 WB Image
WB analysis of whole cell extracts (30 μg lysate) of SH-SY5Y (lane 1), Jurkat (Lane 2), HEK-293 (lane 3), NTERA-2 (Lane 4), and U-87 MG (Lane 5) using GTX79267 ROR alpha antibody. Dilution : 1:1000
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REFERENCE
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REVIEW
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