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ROR gamma antibody

Anti-ROR gamma antibody used in IHC (Paraffin sections) (IHC-P). GTX70885

Cat No. GTX70885

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P, IHC

Reactivity

Human
Package
25 μg ($289)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 22 μg/ml
IHC Assay dependent
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 19 amino acid peptide from ligand-binding domain of human ROR gamma.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

RAR related orphan receptor C , IMD42 , NR1F3 , RORC , RORG , RZRG , RZRGAMMA , TOR , ROR gamma , RORγt

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-ROR gamma antibody used in IHC (Paraffin sections) (IHC-P). GTX70885

GTX70885 IHC-P Image

IHC-P analysis of human thymus tissue using GTX70885 ROR gamma antibody.
Antigen retrival : Heat-induced antigen retrieval

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf