APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
20 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat, Rabbit, Bovine, Dog, Hamster, Chimpanzee, Elephant, Gibbon, Gorilla, Horse, Marmoset, Orangutan, Panda, Tamarin(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 18 amino acid peptide from ligand-binding domain of human ROR Gamma.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375390
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
RAR related orphan receptor C , IMD42 , NR1F3 , RORC , RORG , RZRG , RZRGAMMA , TOR , ROR gamma , RORγt
Cellular Localization
Nucleus
Background
The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX70887 IHC-P Image
IHC-P analysis of brain, glioblastoma tissue using GTX70887 ROR gamma antibody.
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GTX70887 IHC-P Image
IHC-P analysis of lung, non small cell carcinoma tissue using GTX70887 ROR gamma antibody.
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GTX70887 IHC-P Image
IHC-P analysis of human lymph node, hodgkins lymphoma tissue using GTX70887 ROR gamma antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX70887 IHC-P Image
IHC-P analysis of human thymus tissue using GTX70887 ROR gamma antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX70887 IHC-P Image
IHC-P analysis of human breast, carcinoma tissue using GTX70887 ROR gamma antibody. Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
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