GeneTex
United States (US)

RP105 antibody [N2C2], Internal

GTX103761_40688_IHC_19011506_126.jpg
GTX103761_40688_WB_19011506_570.jpg

Cat No. GTX103761

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

74 kDa. ( Note )

Positive Control

HL-60
PROPERTIES

Form

Liquid

Buffer

1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human RP105. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

LY64 antibody, Ly78 antibody, MGC126233 antibody, MGC126234 antibody, RP105 antibody, CD180 antibody, CD180 antigen antibody, "lymphocyte antigen-64, radioprotective, 105kDa antibody", lymphocyte antigen 64 antibody, radioprotective 105 kDa protein antibody, CD180 molecule antibody

Cellular Localization

Cell membrane

Background

CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX103761_40688_IHC_19011506_126.jpg

GTX103761 IHC-P Image

Immunohistochemical analysis of paraffin-embedded CL1-5 xenograft, using RP105(GTX103761) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX103761_40688_WB_19011506_570.jpg

GTX103761 WB Image

Sample (30 ug of whole cell lysate)
A: HL-60
7.5% SDS PAGE
GTX103761 diluted at 1:1000

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169