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RTN3 antibody [10A8]

Anti-RTN3 antibody [10A8] used in IHC (Paraffin sections) (IHC-P). GTX83372
Anti-RTN3 antibody [10A8] used in IHC (Paraffin sections) (IHC-P). GTX83372

Cat. No. GTX83372

Host

Mouse

Clonality

Monoclonal

Clone Name

10A8

Isotype

IgG2a

Application

ICC/IF, IHC-P, ELISA

Reactivity

Human
Package
100 μl ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

113 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of RTN3 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_11173446

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

reticulon 3 , ASYIP , HAP , NSPL2 , NSPLII , RTN3-A1

Cellular Localization

Endoplasmic reticulum membrane,Golgi apparatus membrane

Background

This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012]

Database

Research Area

DATA IMAGES

Anti-RTN3 antibody [10A8] used in IHC (Paraffin sections) (IHC-P). GTX83372

GTX83372 IHC-P Image

IHC-P analysis of human Liver tissue using GTX83372 RTN3 antibody [10A8].

Anti-RTN3 antibody [10A8] used in IHC (Paraffin sections) (IHC-P). GTX83372

GTX83372 IHC-P Image

IHC-P analysis of human lung cancer (left) and breast cancer (right) using GTX83372 RTN3 antibody [10A8].

REFERENCE

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399