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RTN3 antibody [1E11]

Anti-RTN3 antibody [1E11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83351

Cat. No. GTX83351

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1E11

Isotype

 IgG2a

Application

 ICC/IF, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all RTN3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

113 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of RTN3 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

reticulon 3 , ASYIP , HAP , NSPL2 , NSPLII , RTN3-A1

Cellular Localization

Endoplasmic reticulum membrane,Golgi apparatus membrane

Background

This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012]

Database

Research Area

DATA IMAGES

Anti-RTN3 antibody [1E11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83351

GTX83351 ICC/IF Image

ICC/IF analysis of HeLa (A), A431 (B) and THP-1 (C) cells using GTX83351 RTN3 antibody [1E11].
Green : RTN3
Blue: DRAQ5 fluorescent DNA dye

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399