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RUNX2 antibody

Anti-RUNX2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37759
Anti-RUNX2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37759

Cat. No. GTX37759

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Mouse
Package
100 μg ($459)
See all RUNX2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:400-800
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.01M TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 212-290 amino acids of human RUNX2

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

runt related transcription factor 2 , AML3 , CBF-alpha-1 , CBFA1 , CCD , CCD1 , CLCD , OSF-2 , OSF2 , PEA2aA , PEBP2aA

Cellular Localization

Nucleus

Background

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]

Database

Research Area

DATA IMAGES

Anti-RUNX2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37759

GTX37759 IHC-P Image

IHC-P analysis of mouse embryo tissue using GTX37759 RUNX2 antibody.

Anti-RUNX2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37759

GTX37759 IHC-P Image

IHC-P analysis of human whirlbone tissue using GTX37759 RUNX2 antibody.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 459