GeneTex
United States (US)

Rad21 antibody [CM110-2C10]

GTX30641_1448_WB_18121410_191.jpg
GTX30641_1449_WB_18121410_186.jpg

Cat No. GTX30641

Host Mouse
Clonality Monoclonal
Clone Name CM110-2C10
Isotype IgG1
Application WB
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

Specificity/Sensitivity

This antibody is specific for both the nuclear hRad21 protein and the cleaved cytoplasmic hRad21 protein.
PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

An N-terminal fusion protein of the C-terminal fragment of Scc1 subunit human cohesin (amino acids 544-631 of hRad21).

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CDLS4 antibody , HR21 antibody , HRAD21 antibody , MCD1 antibody , NXP1 antibody , SCC1 antibody , hHR21 antibody

Cellular Localization

Nucleus

Background

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX30641_1448_WB_18121410_191.jpg

GTX30641 WB Image

WB analysis of HEK293 cell lysate using GTX30641 Rad21 antibody [CM110-2C10].

GTX30641_1449_WB_18121410_186.jpg

GTX30641 WB Image

WB analysis of HEK293 cell lysate using GTX30641 Rad21 antibody [CM110-2C10].

Package List Price ($)
$ 329