Filter-sterilized PBS, 0.09% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Batch dependent (Please refer to the vial label for the specific concentration.)
The antibody was raised by immunizing chicken with full-size recombinant human Rap51 protein.
From the egg yolk
This antibody was conjugated with Chicken IgY, and the IgY was conjugated with cyanogen bromide-activated Agarose (Sepharose). Chicken IgY antibodies have less backgrounds than mammalian IgG antibodies in immuno-reactions. And 100 μl suspension contains 280 μg of IgY.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
RAD51 recombinase , BRCC5 , FANCR , HRAD51 , HsRad51 , HsT16930 , MRMV2 , RAD51 , RAD51A , RECA , Rad51
Nucleus,Cytoplasm,Perinuclear region,Mitochondrion matrix,Cytoskeleton,Microtubule organizing center,Centrosome
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]