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Rad51B antibody

Cat. No. GTX40242

Host

 Mouse

Clonality

 Monoclonal

Isotype

 IgG2a

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all Rad51B products

APPLICATION

Application Note

WB: Use at an assay dependent dilution. Predicted molecular weight: 38 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

42 kDa. ( Note )

Product Note

Does not recognise Rad51C in total HeLa extracts.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length protein (Human) that has been his-tagged and overexpressed in e.coli.

Purification

IgG fraction
The antibody was purified on a talon affinity column under denaturing conditions, followed by gel purification on a SDS-Page.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

RAD51 paralog B , R51H2 , RAD51L1 , REC2

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399
Custom Conjugations