GeneTex
United States (US)

RasGRP1 antibody

GTX64637_20180530_WB_18121411_121.jpg

Cat No. GTX64637

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
See all RasGRP1 products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000 - 1:2000
Not tested in other applications.

Calculated MW

90 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 598-797 of human RASGRP1 (NP_005730.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

HRASGRP1 Antibody , V Antibody , RASGRP Antibody , RASGRP1 Antibody , CALDAG GEFII Antibody , CALDAG GEFI Antibody

Background

This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX64637_20180530_WB_18121411_121.jpg

GTX64637 WB Image

WB analysis of various samples using GTX64637 RasGRP1 antibody.
Dilution : 1:1000
Loading : 25μg per lane
Package List Price ($)
$ 319