GeneTex
  • Country / Location Selection

United States (US)

Rb (phospho Ser795) antibody [28B5]

Anti-Rb (phospho Ser795) antibody [28B5] used in Western Blot (WB). GTX00683

Cat No. GTX00683

Host

Mouse

Clonality

Monoclonal

Clone Name

28B5

Isotype

IgG2a

Application

WB, ELISA

Reactivity

Human
Package
100 μg ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB ~1 μg/ml
ELISA Assay dependent
Not tested in other applications.

Calculated MW

106 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS, 50% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide containing phospho-Ser795 of human Rb

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

RB transcriptional corepressor 1 , OSRC , PPP1R130 , RB , p105-Rb , pRb , pp110

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Rb (phospho Ser795) antibody [28B5] used in Western Blot (WB). GTX00683

GTX00683 WB Image

WB analysis of various samples using GTX00683 Rb (phospho Ser795) antibody [28B5]. The cell extract were immuno-precipitated with anti-Myc antibody and then analyzed by Western Blot with GTX00683 Rb (phospho Ser795) antibody [28B5].
Lane 1 : H1299 overexpressing Myc-tagged wild-type Rb
Lane 2 : H1299 overexpressing Myc-tagged Rb (S795A)
Lane 3 : H1299 overexpressing Myc-tagged Rb (T821A).

REFERENCE

There are currently no references for Rb (phospho Ser795) antibody [28B5] (GTX00683). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Rb (phospho Ser795) antibody [28B5] (GTX00683). Be the first to share your experience with this product.
Package List Price ($)
$ 359