RbAp46 antibody

Cat. No. GTX33460

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IP, ChIP assay
Reactivity	Human, Mouse, Rat
Package	100 μl ($399)

See all RbAp46 products

Datasheet
Document

View product citations for antibody GTX33460 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500 - 1:2000
IP	1:50 - 1:200
ChIP assay	1:50 - 1:200

Not tested in other applications.

Calculated MW

48 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human RBBP7 (NP_002884.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

RB binding protein 7, chromatin remodeling factor , RbAp46

Cellular Localization

Nucleus

Background

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

Database

Gene ID: 5931 RBBP7
UniProt: Q16576 RBBP7

Research Area

DATA IMAGES

GTX33460 WB Image

WB analysis of various sample lysates using GTX33460 RbAp46 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX33460 ChIP assay Image

ChIP analysis of 293T cell lysate using GTX33460 RbAp46 antibody. The amount of immunoprecipitated DNA was checked by quantitative PCR. Histogram was constructed by the ratios of the immunoprecipitated DNA to the input.

GTX33460 IP Image

IP analysis of MCF-7 cell lysate using GTX33460 RbAp46 antibody.
Antibody amount : 1μg / 200μg lysate
Dilution : 1:1000

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf

Package

List Price ($)

100 μl

$ 399

Qty