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Ready-to-use Apoptosis Inducers (Set of 5)

Cat No. GTX47933

Application

Cell Culture, Control
Package
1 kit ($309)
PRODUCT

Summary

The set contains 5 ready-to-use small molecule reagents that induce apoptosis through different mechanisms. Actinomycin D, an antineoplastic antibiotic, inhibits RNA synthesis. Camptothecin, an inhibitor of nuclear topoisomerase, induces apoptosis in many types of cells. Cycloheximide, an active antibiotic against many yeast and fungi, inhibits protein synthesis. Dexamethasone, an active and highly stable glucocorticoid, probably induces apoptosis by binding and activating the intracellular glucocorticoid receptor. Etoposide, a derivative of podophyllotoxin, inhibits topoisomerase activity.


Kit components (All 1000X):

‧ Actinomycin D (10 mM)

‧ Camptothecin (2 mM)

‧ Cycloheximide (100 mM)

‧ Dexamethasone (10 mM)

‧ Etoposide (100 mM)



Features & Benefits:

‧ Contains all 5 ready-to-use apoptosis inducers above in a kit format

APPLICATION

Application Note

We recommend using 1000X dilutions for inducing apoptosis in Jurkat cells (e.g., Add 1 uL to 1 ml of culture medium). However, the optimal doses may vary for different cells and culture conditions.

PROPERTIES

Form

Liquid

Buffer

All compounds are presented in DMSO.

Storage

Store at -20ºC. Protect from light and moisture.

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

apoptosis inducer sample kit , Inducer of apoptosis

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Package List Price ($)
$ 309