APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 - 2 μg/mL |
| 5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918)
Product Note
RLN3 antibody is human specific. RLN3 antibody is predicted to not cross-react with other members of the Relaxin protein family.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
RLN3 antibody was raised against a 19 amino acid peptide near the center of human RLN3.The immunogen is located within amino acids 80 - 130 of RLN3.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
relaxin 3 , H3 , RXN3 , ZINS4 , insl7
Cellular Localization
Secreted
Background
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. The protein encoded by this gene is a member of the relaxin family. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. It may play a role in neuropeptide signaling processes. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX17243 WB Image
WB analysis of HeLa cell lysate using GTX17243 Relaxin 3 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml
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GTX17243 IHC-P Image
IHC-P analysis of human brain tissue using GTX17243 Relaxin 3 antibody.
Working concentration : 20 μg/ml
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GTX17243 IHC-P Image
IHC-P analysis of human brain tissue using GTX17243 Relaxin 3 antibody.
Working concentration : 5 μg/ml
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REFERENCE
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REVIEW
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