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Renin antibody [3E2B11C4]

Anti-Renin antibody [3E2B11C4] used in IHC (Paraffin sections) (IHC-P). GTX02128

Cat No. GTX02128

Host

Mouse

Clonality

Monoclonal

Clone Name

3E2B11C4

Isotype

IgG2b

Application

IHC-P

Reactivity

Human
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.2 μm filtered PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human Renin protein (GTX01282-pro)

Purification

Purified by Protein A

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

renin , HNFJ2

Cellular Localization

Secreted , Membrane

Background

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Renin antibody [3E2B11C4] used in IHC (Paraffin sections) (IHC-P). GTX02128

GTX02128 IHC-P Image

IHC-P analysis of human kidney (from 2 donors) tissue section using GTX02128 Renin antibody [3E2B11C4].
Dilution : 1:60

REFERENCE

There are currently no references for Renin antibody [3E2B11C4] (GTX02128). Be the first to share your publications with this product.

REVIEW

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