GeneTex
United States (US)

Retinoic Acid Receptor beta antibody

GTX100759_40730_WB_19011506_381.jpg

Cat No. GTX100759

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Positive Control

HepG2

Predict Reactivity

Mouse, Rat, Chicken(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.97mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human Retinoic Acid Receptor beta. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

HAP antibody, NR1B2 antibody, RRB2 antibody, RARB antibody, RAR-beta antibody, retinoic acid receptor beta 2 antibody, RAR-epsilon antibody, retinoic acid receptor beta 4 antibody, retinoic acid receptor beta antibody, retinoic acid receptor beta variant 2 antibody, "retinoic acid receptor, beta polypeptide antibody", retinoic acid receptor beta variant 1 antibody, nuclear receptor subfamily 1 group B member 2 antibody, retinoic acid receptor beta 5 antibody, hepatitis B virus activated protein antibody, HBV-activated protein antibody, "retinoic acid receptor, beta antibody"

Cellular Localization

Isoform Beta-1: Nucleus , Isoform Beta-2: Nucleus , Isoform Beta-4: Cytoplasm

Background

This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX100759_40730_WB_19011506_381.jpg

GTX100759 WB Image

Sample (30 ug of whole cell lysate)
A: HepG2
10% SDS PAGE
GTX100759 diluted at 1:1000

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169