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Retinoic Acid Receptor beta antibody

Anti-Retinoic Acid Receptor beta antibody used in Western Blot (WB). GTX66626
Anti-Retinoic Acid Receptor beta antibody used in IHC (Paraffin sections) (IHC-P). GTX66626

Cat. No. GTX66626

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Retinoic Acid Receptor beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 321-370 of Human RARβ.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

retinoic acid receptor beta , HAP , MCOPS12 , NR1B2 , RARbeta1 , RRB2

Background

This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014]

Database

Research Area

DATA IMAGES

Anti-Retinoic Acid Receptor beta antibody used in Western Blot (WB). GTX66626

GTX66626 WB Image

WB analysis of various samples using GTX66626 Retinoic Acid Receptor beta antibody.
Lane1: SK-OVCAR3 whole cell lysate
Lane2: MCF-7 whole cell lysate
Lane3: C6 whole cell lysate
Lane4: CT26 whole cell lysate
Dilution : 1:500
Loading : 40μg

Anti-Retinoic Acid Receptor beta antibody used in IHC (Paraffin sections) (IHC-P). GTX66626

GTX66626 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX66626 Retinoic Acid Receptor beta antibody.
Dilution : 1:100

REFERENCE

Application Reference

Fu L et al. Bioengineered 2022; 13 (5) : 12847-12862 Deleted in lymphocytic leukemia 2 induces retinoic acid receptor beta promoter methylation and mitogen activated kinase-like protein activation to enhance viability and mobility of colorectal cancer cells.
Application : WB
Reactivity : Human
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399